CAS 1632257-75-0 | ASP4345 Free Base
Name: 5-Chloro-N-methyl-2-oxo-N-[[6-(trifluoromethyl)-1H-benzimidazol-2-yl]methyl]-3(2H)-benzoxazoleacetamide
CAS number: 1632257-75-0
Molecular formula: C19H14ClF3N4O3
Molecular weight: 438.79
EINECS number:
MDL No.：
ASP4345 free base (CAS 1632257-75-0)
High-Purity Dopamine D1 Receptor Modulator & Biochemical Agent
Product Overview
ASP4345 free base is a highly selective and blood-brain barrier-permeable modulator of the dopamine D1 receptor. By binding specifically to the allosteric site of the D1 receptor, this small molecule enhances dopamine activity, making it a prominent research tool in neuropharmacology. It serves as an essential compound for investigating central nervous system disorders, cellular signaling, and cognitive enhancement pathways.
Distinctive Features
- Blood-Brain Barrier Permeability: Demonstrates excellent brain penetration capabilities, enabling effective target engagement in neurobiology models.
- Allosteric Modulation: Operates via allosteric activation mechanisms to selectively potentiate endogenous dopamine signaling without direct receptor desensitization.
- Rigorous Quality Assurance: Synthesized and purified under strict analytical controls to guarantee high purity, delivering highly reproducible experimental data.
- Optimal Formulation Stability: Exhibits robust chemical stability in organic research solvents like DMSO, facilitating effortless laboratory stock preparation.
Target Applications
Synonyms / Alternative Names
ASP4345 free base; ASP-4345; ASP4345; 5-Chloro-N-methyl-2-oxo-N-[[6-(trifluoromethyl)-1H-benzimidazol-2-yl]methyl]-3(2H)-benzoxazoleacetamide.
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