1642288-47-8 Mavacamten

Properties

Appearance White to off-white solid
Density 1.19±0.1 g/cm3
solubility insoluble in H2O; ≥11.32 mg/mL in EtOH with ultrasonic; ≥13.65 mg/mL in DMSO
pka8.83±0.40

 

Application:

    Mavacamten is a small molecule drug used to treat obstructive hypertrophic cardiomyopathy (HCM), which reduces myocardial hypertrophy and improves cardiac function by inhibiting the function of myocardial myofibril forming enzyme (Myosin)

 

Synonyms:

Mavacamten

1642288-47-8

Camzyos

MYK-461

SAR-439152

6-[[(1S)-1-phenylethyl]amino]-3-propan-2-yl-1H-pyrimidine-2,4-dione

2,4(1H,3H)-Pyrimidinedione, 3-(1-methylethyl)-6-(((1S)-1-phenylethyl)amino)-

6-(((1S)-1-Phenylethyl)amino)-3-(propan-2-yl)-1,2,3,4 tetrahydropyrimidine-2,4-dione

6-[[(1~{S})-1-phenylethyl]amino]-3-propan-2-yl-1~{H}-pyrimidine-2,4-dione

(S)-3-isopropyl-6-((1-phenylethyl)amino)pyrimidine-2,4(1H,3H)-dione

mavacamtenum

2,4(1H,3H)-Pyrimidinedione, 3-(1-methylethyl)-6-[[(1S)-1-phenylethyl]amino]-

3-(1-Methylethyl)-6-(((1S)-1-phenylethyl)amino)-2,4(1H,3H)-pyrimidinedione

6-(((1S)-1-phenylethyl)amino)-3-(propan-2-yl)pyrimidine-2,4(1H,3H)-dione

Camzyos

Mavacamten

 

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