CAS 1374024-48-2 | Rimegepant Sulfate
Name: Rimegepat sulfate
CAS number: 1374024-48-2
Molecular formula: C28H30F2N6O7S
Molecular weight: 632.64
EINECS number: 822-372-0
MDL No.：
Product Overview
Rimegepant Sulfate (CAS 1374024-48-2) is a small-molecule calcitonin gene-related peptide (CGRP) receptor antagonist. Appearing as a white to off-white solid powder, it functions as an active pharmaceutical ingredient (API) in therapeutic formulations designed for targeted neurological treatments. It features structural stability and precise binding affinity for receptor-targeted synthetic research.
Technical Specifications
| Chemical Name | Rimegepant Sulfate / BHV-3000 hemisulfate |
| CAS Number | 1374024-48-2 |
| EINECS Number | 822-372-0 |
| Molecular Formula | C28H30F2N6O7S |
| Molecular Weight | 632.64 g/mol |
| Purity (HPLC) | ≥ 98.0% / API Grade |
| Appearance | White to off-white solid powder |
| Solubility | Soluble in DMSO and methanol; sparingly soluble in water |
Main Properties
- Targeted Antagonism: Demonstrates high potency and selectivity for human CGRP receptors.
- Solid State Stability: The sulfate salt form provides enhanced crystalline stability and physical properties compared to the free base.
- Formulation Ready: Optimized particle characteristics support uniform blending and process consistency in pharmaceutical manufacturing.
Synonyms & Chemical Identifiers
Synonyms: Rimegepant sulfate salt, BMS-927711 sulfate, BHV-3000 hemisulfate, Nurtec sulfate, (5S,6S,9R)-5-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl 4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxylate sulfate.
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