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CAS 1169766-01-1 | Ramatercept

CAS 1169766-01-1 | Ramatercept

Name: Ramatercept
CAS number: 1169766-01-1
Molecular formula:
Molecular weight: 0
EINECS number:
MDL No.:

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Description

Product Overview

Ramatercept (CAS 1169766-01-1) is a soluble activin receptor type IIB (ActRIIB) fusion protein designed to function as an ACVR2 antagonist. By neutralizing myostatin and related ligands, it prevents negative regulation of muscle growth. This recombinant therapeutic candidate offers high specificity for advanced biopharmaceuticals and preclinical research.

Technical Specifications

Product Name Ramatercept
CAS Registry Number 1169766-01-1
Molecular Weight ~77.24 kDa
Product Type Recombinant Fusion Protein / ActRIIB Antagonist
Purity Grade ≥95.0% (SEC-HPLC / SDS-PAGE)
Physical Form Lyophilized powder or solution
Storage Conditions Store at -20°C to -80°C; avoid repeated freeze-thaw cycles

Applications & Usage

  • Investigated in therapeutic studies for neuromuscular disorders, including muscular dystrophy and muscle wasting conditions.
  • Utilized as a targeted inhibitor in TGF-beta signaling pathway investigations.
  • Serves as a reference standard in biotechnology assay development and bioanalytical validation.
  • Applied in biopharmaceutical research focused on bone density and muscle mass enhancement.

Synonyms & Identifiers

ACE-031; ActRIIB-Fc fusion protein; Soluble Activin Receptor Type IIB-Fc; Recombinant Human ActRIIB-Fc.

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