CAS 1428333-96-3 | Pritelivir Mesylate
Name: BAY57-1293 mesylate; Pritelivir mesylate
CAS number: 1428333-96-3
Molecular formula: C19H22N4O6S3
Molecular weight: 498.59
EINECS number:
MDL No.：MFCD32671320
Specification:
| Appearance | White to Off-White powder |
| Purity (HPLC) | NLT 98% |
| Usage | Potently inhibits the ATPase activity of the HSV helicase‑primase enzyme complex, blocking viral DNA replication and virus multiplication. |
| Applications |
• Anti‑HSV research: In vitro and in vivo studies of herpes simplex virus infections. • Acyclovir‑resistant HSV: Active against acyclovir‑resistant HSV strains. • Animal models: Lethal disseminated herpes, zosteriform cutaneous herpes, ocular herpes. • Potential clinical use: Investigational for severe/life‑threatening HSV infections (encephalitis, mucocutaneous, genital herpes). |
| Intermediates |
1. 4‑Methyl‑5‑sulfamoyl‑2‑aminothiazole 2. N‑Methyl‑4‑methyl‑5‑sulfamoyl‑2‑aminothiazole 3. Methyl 2‑(4‑(pyridin‑2‑yl)phenyl)acetate / 2‑(4‑(pyridin‑2‑yl)phenyl)acetic acid 4. N‑[5‑(Aminosulfonyl)‑4‑methyl‑1,3‑thiazol‑2‑yl]‑N‑methyl‑2‑[4‑(2‑pyridinyl)phenyl]acetamide |
Synonyms:
AIC316 mesylate
Pritelivir mesylate
BAY57-1293 mesylate
Pritelivir mesylate (BAY 57-1293)
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