CAS 1228538-47-3 | Quilizumab

Quilizumab

CAS No: 1228538-47-3 | Molecular Type: Monoclonal Antibody (IgG) | Target: IgE B-cell receptor

Synonyms / Alternative Names

• Anti-IgE Monoclonal Antibody
• Quilizumab mAb
• Humanized IgG1κ antibody targeting membrane-bound IgE

Appearance & Physicochemical Properties

• Appearance: Clear to slightly opalescent solution
• Formulation: Typically in phosphate-buffered saline (PBS)
• Solubility: Soluble in aqueous buffers
• Stability: Store at 2–8°C; avoid repeated freeze-thaw cycles
• Protein Type: Humanized monoclonal IgG1 antibody

Specifications & Packaging

• Purity: >95% (by SDS-PAGE / HPLC)
• Form: Liquid or lyophilized powder
• Packaging: 1 mg / 5 mg / 10 mg vials (customizable)
• Storage: Refrigerate 2–8°C; lyophilized form stable for longer-term storage

Applications

• Research on IgE-mediated allergic diseases
• Investigating B-cell modulation and immunotherapy
• Preclinical studies for asthma and other IgE-related disorders

Safety & Handling

• Use appropriate personal protective equipment (PPE)
• Handle under sterile conditions to avoid contamination
• Do not ingest; avoid contact with eyes and skin
• Follow institutional biosafety guidelines for antibody handling

Additional Information

• Quilizumab is a humanized monoclonal antibody developed for IgE-targeted therapy
• Used primarily in research settings, not approved for general clinical use
• Commonly supplied in PBS for experimental studies