873054-44-5 Ivacaftor (vx-770)
Product name:Ivacaftor (VX-770)
CAS:873054-44-5
MF:C24H28N2O3
MW:392.49
EINECS:
MDL No.:MFCD17171361
Application:
Ivacaftor is a enhancer of CFTR protein. The CFTR protein is a chloride ion channel present on the surface of epithelial cells in multiple organs. Ivacaftor facilitates chloride transport by enhancing the channel opening probability (or gating) of CFTR protein. Ivacaftor can be used to treat cystic fibrosis
Synonyms:
Ivacaftor
873054-44-5
VX-770
Kalydeco
Ivacaftor (VX-770)
N-(2,4-di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide
Ivacaftor-d18
ivacaftorum
N-[2,4-Bis(tert-butyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide
CHEBI:66901
1413431-05-6
UNII-1Y740ILL1Z
1Y740ILL1Z
MFCD17171361
| Properties |
Safety Information |
Statements |
|
Melting point:212-215°C Boiling point:550.4±50.0 °C(Predicted) Density 1.187 storage temp. Refrigerator solubility DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) form Solid pka11.08±0.23(Predicted) color White to Light Brown |
Symbol(GHS) GHS08,GHS07 Signal word Warning |
Hazard statements H361-H319-H315-H335 Precautionary statements P264-P280-P302+P352-P321-P332+P313-P362-P201-P202-P281-P308+P313-P405-P501-P264-P280-P305+P351+P338-P337+P313P |
Package:
Our products generally use double-layer packaging to ensure product sealing and quality. Specific packaging can also be provided for the product according to customer requirements.
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