CAS 4579-64-0 | D-lysergic Acid Methyl Ester
CAS:4579-64-0
MF:C17H18N2O2
MW:282.34
EINECS:224-964-9
MDL No.:MFCD07368163
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Description
Product Overview
Methyl Ergoline Acid (D‑Lysergic Acid Methyl Ester) is a main ergoline‑derived pharmaceutical intermediate, primarily used for synthesizing dopamine agonists and ergot alkaloid‑based drugs. It is a controlled precursor due to its structural relation to lysergic acid derivatives.
Basic Information
| Item | Details |
|---|---|
| CAS No. | 4579‑64‑0 |
| IUPAC Name | Methyl (6aR,9R)‑7‑methyl‑4,6,6a,7,8,9‑hexahydroindolo[4,3‑fg]quinoline‑9‑carboxylate |
| Synonyms | D‑Lysergic Acid Methyl Ester, Methyl Lysergate, NSC 157966 |
| Physical State | Off‑white to dark solid |
| Melting Point | 131–139 °C (decomposes) |
| Boiling Point | 469.0 ± 45.0 °C (predicted) |
| Density | 1.30 ± 0.1 g/cm³ |
| Purity (Typical) | ≥98% (HPLC) |
| Application Category | Detailed Uses |
|---|---|
| Pharmaceutical Intermediate | - Main precursor for cabergoline (dopamine D₂ agonist, treats hyperprolactinemia)- Intermediate for bromocriptine, pergolide, and other ergot‑derived antiparkinsonian drugs- Building block for serotonin (5‑HT) receptor ligands and CNS research compounds |
| Research & Development | - Tool compound for studying 5‑HT₂A and dopamine receptor pharmacology- Reference standard for analytical testing (HPLC, LC‑MS) in API synthesis- Precursor for novel psychedelic and neuropsychiatric drug discovery |
| Veterinary Medicine | - Limited use in veterinary dopamine agonists for reproductive disorders in livestock , use accdoing to local law. |
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