CAS 247062-33-5 | Abaloparatide; Abaloparatide Acetate
Name: Abaloparatide
CAS number: 247062-33-5
Molecular formula: C174H300N56O49
Molecular weight: 3960.5896
EINECS number: 218-362-5
MDL No.：
Abaloparatide (CAS 247062-33-5)
Product Overview
Abaloparatide is a synthetic 34-amino acid peptide analog of human parathyroid hormone-related protein (PTHrP[1-34]). Manufactured as a high-purity active pharmaceutical ingredient (API), it acts as a selective activator of the parathyroid hormone 1 receptor (PTH1R) pathway to stimulate bone formation and osteoblast activity.
Applications
- Osteoporosis & Bone Metabolism Research: Investigated for promoting anabolic bone mass density (BMD) accretion and microarchitectural restoration.
- Pharmaceutical API Development: Formulated as a reference active substance for subcutaneous injection solutions and metabolic bone disease therapies.
- Receptor Signaling Studies: Utilized in cell-based bioassays to analyze PTH1R selective binding conformations and downstream cAMP activation.
- Analytical Quality Control: Applied as a peptide reference standard in LC-MS identification, purity testing, and peptide sequence verification.
Storage & Handling
- Keep container tightly sealed under inert atmosphere (nitrogen or argon).
- Recommended storage temperature: -20°C (desiccated) for long-term stability.
- Protect from ambient moisture, heat, and repeated freeze-thaw cycles.
Synonyms & Identifiers
Abaloparatide | Tymlos | BA058 | BIM-44058 | CAS 247062-33-5 | UNII-88Q6K4D7A1
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