274693-27-5 Ticagrelor

Properties

Appearance White to Off-White Solid
Melting point:138-140°C
Boiling point:777.6±70.0 °C
Density 1.67
solubility Methanol (Slightly)
pka13.26±0.70
optical activity[α]/D -55 to -65°, c =0.2 in methanol
Stability:Hygroscopic

 

Application:

Ticagrelor

274693-27-5

Brilinta

Brilique

Possia

(1S,2S,3R,5S)-3-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

1,2-Cyclopentanediol,3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-,(1S,2S,3R,5S)-

(1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-propylsulfanyltriazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor Form

TICAGRELOR (EP MONOGRAPH)

TICAGRELOR [EP MONOGRAPH]

compound 17 (PMID: 17827008)

compound 17 [PMID: 17827008]

(1S,2S,3R,5S)-3-(7-{[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino}-5-(propylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

(1S,2S,3R,5S)-3-[7-[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropylamino]-5-(propylthio)- 3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

ticagrelorum

Brilinta 

Ticagrelor (Standard)

 

 

 

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