1629229-37-3 Fezolinetant

Properties

Appearance White to yellow Solid
Boiling point:623.0±65.0 °C
Density 1.56±0.1 g/cm3
storage temp. Store at -20°C
solubility DMSO:20.0(Max Conc. mg/mL);55.8(Max Conc. mM)
pka-0.28±0.40

 

Application:

     Fezolinatant (trade name VEOZAH) is a non hormonal medication used to treat moderate to severe vasomotor symptoms (VMS) caused by menopause. It is an NK3 receptor antagonist that primarily regulates neuronal activity in the thermoregulatory center by antagonizing the neurokinin-3 receptor (NK3 receptor), thereby alleviating VMS symptoms

 

Synonyms:

Fezolinetant

1629229-37-3

ESN364

VEOZAH

ESN-364

fezolinetantum

A2693

(4-fluorophenyl)-[(8R)-8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]methanone

(R)-(4-fluorophenyl)(8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanone

A-2693

AS-3472693-00

Methanone, ((8R)-5,6-dihydro-8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-1,2,4-triazolo(4,3-a)pyrazin-7(8H)-yl)(4-fluorophenyl)-

(4-FLUOROPHENYL)((8R)-5,6-DIHYDRO-8-METHYL-3-(3-METHYL-1,2,4-THIADIAZOL-5-YL)-(1,2,4)TRIAZOLO(4,3-A)PYRAZIN-7(8H)-YL)METHANONE

Veoza

Vezoa

GTPL10422

ESN 364

 

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