120011-70-3 Donepezil Hydrochloride

Properties

Appearance white to off-white powder
Melting point:220-222°C
storage temp. room temp
Water Solubility Soluble in water
solubility insoluble in EtOH; insoluble in DMSO; ≥10.4 mg/mL in H2O
Stability:Hygroscopic

 

Application:

Donepezil hydrochloride is suitable for the treatment of mild or moderate symptoms of Alzheimer's dementia.

generics. The detailed information is shown in the following English table.

Category

Details

Applications

1. Alzheimer's Disease: Approved for mild, moderate, and severe dementia of the Alzheimer's type, improving cognitive function (memory, attention), daily living activities, and behavioral symptoms. 2. Vascular Dementia : Used to improve cognitive decline secondary to cerebrovascular disease, with clinical evidence supporting efficacy in some patients. 3. Lewy Body Dementia : Relieves cognitive fluctuations and neuropsychiatric symptoms (e.g., hallucinations, parkinsonism) in some regions.. 4. Down Syndrome-Associated Dementia : Investigated for early cognitive impairment in adults with Down syndrome (limited clinical data).

---

 

 

Synonyms:

Donepezil hydrochloride

120011-70-3

Donepezil HCl

Aricept

110119-84-1

BNAG

2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one hydrochloride

Aricept ODT

2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one hydrochloride

1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-, hydrochloride (1:1)

1-Benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine hcl

2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one;hydrochloride

(+-)-2-((1-Benzyl-4-piperidyl)methyl)-5,6-dimethoxy-1-indanone hydrochloride

1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-((1-(phenylmethyl)-4-piperidinyl)methyl)-, hydrochloride

Donepezil hydrochloride (USAN:USP)

2-(1-Benzyl-4-piperidylmethyl)-5,6-dimethoxy-1-indanone Hydrochloride

2-(1-Benzyl-piperidin-4-ylmethyl)-5,6-dimethoxy-indan-1-one hydrochloride

CAS-120011-70-3

1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-, hydrochloride

Donepezil Hydrochloride; 1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-, hydrochloride (9CI); Aricept; Aricept 

Donepezil HCl 

Donepezil (Hydrochloride) 

 

 

Hot Tags: 120011-70-3 donepezil hydrochloride, China 120011-70-3 donepezil hydrochloride manufacturers, suppliers, Phenazine, 2 TRIBUTYLSTANNYL PYRIDINE, Rhodizonicacidsodiumsalt, Pyrimidinetetramine sulfate, Intermediate, Chlorophosphonazo III