1092939-17-7 Ruxolitinib Phosphate

Properties

Appearance White to Off-White Solid
Melting point:186-190°C
storage temp. Refrigerator
solubility DMSO (Slightly), Methanol (Slightly)
 

Application:

    Lukotinib is an anti-tumor drug that has good therapeutic effects on tumor diseases caused by low self immunity, pathogenic bacterial infections, and genetic factors. It can effectively inhibit the growth of tumor cells. Clinically, it can be mainly used for adult patients with moderate to high-risk primary myelofibrosis (PMF) (also known as chronic idiopathic myelofibrosis), myelofibrosis secondary to polycythemia vera (PPV-MF), or myelofibrosis secondary to primary thrombocytopenia (PET-MF), to treat related diseases, splenomegaly, or disease-related symptoms.

Synonyms:

Jakafi
INCB 018424
Ruxolitinib
Roxolitinib
incb-018424
β-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyriMidin-4-yl)-(βR)-1H-pyrazole-1-propanenitrile
(R)-3-(4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile
(3R)-3-cyclopentyl-3-(4-{7H-pyrrolo[2,3-d]pyriMidin-4-yl}-1H-pyrazol-1-yl)propanenitrile
(3R)-3-(4-(7H-pyrrolo[2,3-d]pyriMidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile
(betaR)-beta-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile
(betar)-beta-cyclopentyl-4-(7h-pyrrolo(2,3-d)pyrimidin-4-yl)-1h-pyrazole-1-propanenitrile
 

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