
CAS 5709-98-8 | (R)-(+)-3-CYCLOHEXENECARBOXYLIC ACID
Name: (R)-(+)-3-CYCLOHEXENECARBOXYLIC ACID
CAS number: 5709-98-8
Molecular formula: C7H10O2
Molecular weight: 126.15
EINECS number: 232-629-3
MDL No.:MFCD08275445
Product Overview
(R)-(+)-3-Cyclohexenecarboxylic acid is a chiral unsaturated carboxylic acid featuring a defined (R)-stereocenter and a reactive cyclohexene ring. Serving as a versatile chiral building block, it enables precise asymmetric synthesis, structural modification of bioactive compounds, and specialized polymer formulation.
Pharmaceutical Discovery & Lead Synthesis
- Acts as an enantiopure scaffold for constructing alicyclic drug candidates and enzyme inhibitor structures.
- Introduces defined 3D stereochemistry to small molecules, facilitating optimization of target binding affinity.
- Provides a reactive carboxylate site for amide couplings, esterifications, and peptidomimetic designs.
Asymmetric Synthesis & Catalysis
- Utilized in organic synthesis to introduce chiral cyclohexyl derivatives without requiring resolution steps.
- Functions as a precursor for chiral ligands, auxiliaries, and organocatalysts used in asymmetric transformations.
- Enables stereoselective ring-opening, epoxidation, and dihydroxylation reactions across the double bond.
Advanced Materials & Fine Chemicals
- Serves as a chiral monomer for bio-based or optoelectronic functional polymers with controlled spatial configuration.
- Used in photo-curable resins, liquid crystal intermediates, and performance polymer additives.
- Enables cross-linking and polymerization studies via olefin metathesis and radical reactions.
Handling & Lab Applications
Suitable for early-stage medicinal chemistry pipelines, academic synthetic research, and custom CRO synthesis. Store in a cool, well-ventilated location sealed tightly under inert atmosphere to protect double-bond integrity and prevent moisture uptake.
Synonyms
(R)-Cyclohex-3-enecarboxylic acid; | (1R)-Cyclohex-3-ene-1-carboxylic acid; | (+)-(R)-3-Cyclohexenecarboxylic acid; | (R)-3-Cyclohexene-1-carboxylic acid
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