CAS 519-37-9 | 7-(β-Hydroxyethyl)theophylline

Application:

This product can be used as an intermediate for Etofylline clofibrate.

 

Route of Synthesis:

Description for route of synthesis:

     Add theophylline into the reaction vessel, using n-propanol as the solvent and pyridine as the alkaline catalyst, stir and heat to the set temperature to dissolve theophylline; Then slowly introduce ethylene oxide and continue the reaction at this temperature until the raw material is completely converted; After the reaction is completed and cooled, the crude product is recrystallized, filtered, washed, and vacuum dried to obtain the target product β - hydroxyethyl theophylline.

 

Synonyms:

ETOFYLLINE
BIOPHYLLINE

 

7-(2-Hydroxyethyl)theophylline
Phyllocormin

7-(β-Hydroxyethyl)theophylline
ETOFYLLINE EPE
BETA-HYDROXYETHYLTHEOPHYLLINE

 

7-(2-Hydroxyethyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
ETOFYLLINE (BETA-HYDROXYETHYLTHEOPHYLLINE)

 

B-hydroxyethyltheophylline

 

 

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