CAS 261953-36-0 | 6-Iodo-1H-indazole

6-Iodo-1H-indazole (CAS 261953-36-0)

Halogenated Indazole Heterocycle & Synthetic Intermediate

Product Overview

6-Iodo-1H-indazole (CAS 261953-36-0) is a functionalized bicyclic indazole derivative containing an iodine substituent at the C-6 position. Manufactured under controlled chemical synthesis procedures, this halogenated heterocyclic compound functions as a building block for palladium-catalyzed cross-coupling reactions, active pharmaceutical ingredient (API) pathways, and targeted medicinal chemistry investigations.

Distinctive Features

• Reactive C-6 Iodine Motif: Provides a versatile site for transition-metal-catalyzed C-C, C-N, and C-O bond forming reactions such as Suzuki-Miyaura and Buchwald-Hartwig couplings.
• Functional Indazole Ring: The N-1 and N-2 positions on the indazole ring allow selective alkylation or protection strategies during multi-step organic synthesis.
• Monitored Purity Profile: Standardized analytical characterization ensures controlled residual halide limits and consistent batch performance.
• Organic Solvent Solubility: Demonstrates compatibility with standard organic solvents like dimethyl sulfoxide (DMSO), methanol, and tetrahydrofuran (THF) for practical synthetic processing.

Target Applications

Synonyms / Alternative Names

6-Iodoindazole; 1H-Indazole, 6-iodo-; 6-Iodo-1H-indazo; 6-Iodo-2H-indazole.