2144-08-3 2,3,4-trihydroxybenzaldehyde

Specification:

Appearance	Light yellow crystalline powder
Content	99.5% min
Water .Loss on Drying,	0.20% max
Melting point, ℃	161-163℃
Residue on ignition	0.1% max
Arsenic	3ppm max
Lead	2ppm max
Heavy Metal(Pb) (Ug/g)	20 ppm max

 

Application:

Dye: It can be used as a raw material for certain organic dyes.
Analytical Chemistry: 2,3,4-trihydroxybenzaldehyde can be used in color reactions to determine the presence of certain metal ions.

Downstream Application Field	Specific Products	Product Description
Pharmaceutical Synthesis	Pharmaceutical intermediates (e.g., anti-inflammatory drugs, antioxidant agents, antibacterial APIs), API precursors	2,3,4-Trihydroxybenzaldehyde acts as a key aromatic building block in pharmaceutical synthesis. Its three hydroxyl groups (-OH) and aldehyde group (-CHO) enable diverse reactions (e.g., condensation, cyclization, reduction, nucleophilic addition), facilitating the synthesis of bioactive molecules. It is widely used in developing antioxidant drugs (targeting free radical scavenging) and anti-inflammatory agents, as the polyhydroxyl structure enhances antioxidant activity and biological compatibility, while the aldehyde group enables precise structural modification of APIs to improve target binding affinity.
Agrochemicals	Pesticide intermediates (e.g., fungicides, insecticides, plant growth regulators), herbicide precursors	It serves as a precursor for synthesizing high-efficiency agrochemicals. Through chemical modifications (e.g., esterification, amidation, Schiff base formation), it can be converted into active ingredients with enhanced pesticidal activity, selectivity, and environmental biodegradability. These products effectively control plant pathogens (fungi, bacteria) and pests, while some derivatives act as plant growth regulators to improve crop stress resistance (drought, disease). The polyhydroxyl structure enhances the compound's adhesion to plant surfaces and absorption, improving bioavailability.
Dyes & Pigments	Natural dyes, synthetic dyes (e.g., azo dyes, flavonoid-based dyes), pigment intermediates	It is used as a raw material for synthesizing dyes and pigments, especially for products requiring antioxidant and light-fast properties. Through coupling reactions (e.g., azo coupling) and condensation reactions, it produces dyes with bright colors (e.g., yellow, brown, red) for textiles, paper, and food coloring. The polyhydroxyl groups improve dye solubility and color fastness (to light, water, and chemicals), making it suitable for high-performance industrial dyes and natural food colorants.
Cosmetics & Personal Care	Antioxidant serums, moisturizing creams, anti-aging lotions, skin brightening products	As a natural-derived antioxidant and humectant, it is used in cosmetic formulations to scavenge free radicals, reduce oxidative stress on skin, and delay aging (e.g., fine lines, dark spots). Its hydroxyl groups attract and retain moisture, improving skin hydration and barrier function. It is compatible with other cosmetic ingredients (e.g., vitamins, plant extracts) and suitable for sensitive skin products, providing a gentle, non-irritating anti-aging and moisturizing effect.
Fine Chemicals	Functional organic derivatives (e.g., Schiff bases, benzodioxane derivatives, polyhydroxy aldehyde polymers), specialty intermediates	It is a versatile intermediate for synthesizing fine chemicals. Through condensation with amines, it forms Schiff bases used as corrosion inhibitors, catalysts, and chelating agents. Benzodioxane derivatives derived from it are applied in polymer modifiers, fragrance intermediates, and specialty solvents. The compound's high reactivity also makes it a raw material for synthesizing polyhydroxy polymers with applications in ion-exchange resins and biodegradable materials.
Food & Feed Additives	Natural antioxidants, food preservatives, feed quality improvers	Food-grade 2,3,4-Trihydroxybenzaldehyde is used as a natural antioxidant and preservative in food and feed products. It inhibits lipid oxidation and microbial growth, extending the shelf life of oils, snacks, and animal feed. It is compatible with food matrices, non-toxic, and compliant with food safety standards (e.g., FDA, EU regulations), making it an alternative to synthetic antioxidants (e.g., BHA, BHT).
Laboratory & R&D	Organic synthesis reagents, antioxidant research tools, natural product derivatives	High-purity grades are used as research reagents in academic institutions and industrial R&D laboratories. They are employed to develop novel synthetic routes for polyhydroxy compounds, study antioxidant mechanisms, and prepare natural product derivatives for pharmaceutical and cosmetic research. The compound's unique polyhydroxyl-aldehyde structure makes it a valuable tool for exploring new functional materials and bioactive molecules.

 

 

Synonyms:

2,3,4-Trihydroxybenzaldehyde

2144-08-3

Benzaldehyde, 2,3,4-trihydroxy-

Pyrogallol-4-carboxaldehyde

3,4-Dihydroxysalicylaldehyde

2,4-Trihydroxybenzaldehyde

Benzaldehyde,3,4-trihydroxy-

2,3,4-trihydroxy-benzaldehyde

 

 

 

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