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CAS 85118-33-8 | Gaboxadol Hydrochloride

CAS 85118-33-8 | Gaboxadol Hydrochloride

Name: GABOXADOL HYDROCHLORIDE
CAS number: 85118-33-8
Molecular formula: C6H9ClN2O2
Molecular weight: 176.6
EINECS number: 285-687-7
MDL No.:MFCD00055180

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Description

Gaboxadol Hydrochloride (CAS 85118-33-8)

High-purity GABA-A receptor agonist designed for advanced neuropharmacological research and biochemical applications.

Technical Specifications

Chemical Name: 4,5,6,7-Tetrahydroisoxazolo[5,4-c]pyridin-3-ol hydrochloride
CAS Number: 85118-33-8
Molecular Formula: C6H9ClN2O2 (C6H8N2O2 · HCl)
Molecular Weight: 176.60 g/mol
Appearance: White to off-white crystalline powder
Purity (HPLC): ≥ 98.0%

Primary Applications

  • Acts as a selective agonist targeting extrasynaptic GABA-A receptors containing the δ subunit.
  • Utilized in patch-clamp electrophysiology to isolate tonic inhibitory conductances in central nervous system tissues.
  • Serves as a specialized tool for non-REM sleep architecture and delta wave activity modeling.
  • Applied in neuropharmacological assays evaluating non-opioid antinociceptive pathways.

Handling & Storage

Store at room temperature in a cool, dry, and light-protected environment. Ensure containers remain tightly sealed when not in use. Highly soluble in aqueous solutions and standard physiological buffers.

Synonyms

THIP hydrochloride; THIP HCl; Lu 02-030 hydrochloride; MK-0928; OV101; 4,5,6,7-Tetrahydroisoxazolo[5,4-c]pyridin-3-ol Hydrochloride

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