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CAS 144885-51-8 | Sodium Mercaptododecaborate (BSH)

CAS 144885-51-8 | Sodium Mercaptododecaborate (BSH)

Name: Sodium mercaptododecaborate
CAS number: 144885-51-8
Molecular formula: B12H12Na2S
Molecular weight: 219.87
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Description

Product Overview

Sodium mercaptododecaborate (BSH, CAS 144885-51-8) is a boron-rich polyhedral cluster compound containing a thiol functional group. It serves as a targeted boron delivery agent in Boron Neutron Capture Therapy (BNCT) biomedical research and acts as a specialized inorganic building block for functional boron cluster chemistry.

Primary Applications & Characteristics

  • BNCT Oncology Research: Utilized in targeted radiation therapy studies, supplying high boron density (12 boron atoms per cluster) to accumulate selectively within target tumor cells.
  • Bioconjugation & Delivery Systems: The reactive sulfhydryl (-SH) group allows chemical conjugation with liposomes, nanoparticles, antibodies, or peptides for targeted cellular delivery.
  • Boron Cluster Synthesis: Applied as an intermediate in inorganic and medicinal chemistry for constructing polyhedral borane derivatives and supramolecular frameworks.
  • Aqueous Solubility: The sodium salt formulation offers high water solubility, facilitating preparation in biological buffers and physiological solutions.

Synonyms & Commercial Names

BSH; Sodium mercaptododecaborate; Disodium mercaptoundecahydro-closo-dodecaborate; Disodium mercaptododecaborate; Sodium borocaptate

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