CAS 122320-73-4 | Rosiglitazone

CAS 122320-73-4 (Rosiglitazone) is a high-purity synthetic compound belonging to the thiazolidinedione class. Developed as a potent and selective agonist for the peroxisome proliferator-activated receptor-gamma (PPAR-γ), this reference material serves as an essential tool in biochemical research and pharmaceutical development for investigating metabolic regulation and cellular pathways.

Synonyms & Alternative Names

Rosiglitazona, 5-[[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione, BRL 49653, Rosiglitazone free base.

Specifications & Properties

• Product Name: Rosiglitazone
• CAS Number: 122320-73-4
• Molecular Formula: C18H19N3O3S
• Molecular Weight: 357.43
• EINECS Number: 924-121-1
• MDL Number: MFCD00871760
• Solubility & Form: Solid powder; soluble in organic solvents such as DMSO and ethanol; insoluble in water.

Applications

• Biochemical and Physiological Research Utilized as a reference substance and screening compound in laboratory studies focused on insulin sensitivity, fatty acid storage, and glucose homeostasis mechanisms.
• Pharmaceutical Development Intermediates Serves as an advanced chemical intermediate or base element for the synthesis and investigation of derived metabolic and therapeutic molecular structures.
• Cellular Signaling Assays Employed in in vitro cell culture applications to observe gene transcription modifications linked to adipose tissue differentiation and inflammatory response control.