CAS 16937-99-8 | BOC-D-Leucine Monohydrate

Specification:

Appearance	White powder
Purity	98%+

 

Application:

4-trifluoromethoxy-trifluoroethoxy-5-chloroaniline is an intermediate of the insecticide fluorourea. BOC-D-leucine is mainly used in the field of organic synthesis. As a protective group in peptide synthesis, it can protect the amino and carboxyl groups of leucine to prevent them from undergoing unwanted chemical reactions. BOC-D-leucine can be easily removed through acid hydrolysis in the synthesis of peptides or proteins.

Peptide Synthesis 

   Used as a protected monomer for solid‑phase peptide synthesis (SPPS) and solution‑phase peptide synthesis.

The BOC group serves as an amine‑protecting group, selectively removable under acidic conditions (e.g., TFA) without racemization.

Pharmaceutical Intermediate

   Building block for synthetic peptide APIs, peptidomimetics, and chiral small‑molecule drugs.

Incorporated into drug candidates to improve metabolic stability, receptor selectivity, and bioavailability.

Chiral Ligand & Catalyst Precursor

   Used in preparing chiral catalysts, auxiliaries, and ligands for asymmetric synthesis.

Biochemical Research

   Applied in peptide‑based probe design, enzyme substrate studies, and structure–activity relationship (SAR) research.

 

Synonyms:

16937-99-8

Boc-D-Leu-OH

Boc-D-leucine

N-[(1,1-Dimethylethoxy)carbonyl]-D-leucine; N-Carboxy-D-leucine N-tert-Butyl Ester; (R)-2-(tert-Butoxycarbonylamino)-4-methylpentanoic Acid; D-Boc Leucine; N-(tert-Butoxycarbonyl)-D-leucine; tert-Butoxycarbonyl-D-leucine

N-Boc-D-leucine

N-(tert-Butoxycarbonyl)-D-leucine

(R)-2-((tert-Butoxycarbonyl)amino)-4-methylpentanoic acid

(2R)-2-{[(Tert-Butoxy)Carbonyl]Amino}-4-Methylpentanoic Acid

(2R)-4-methyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoic acid

Boc-D-Leu-OH hydrate

D-Boc leucine

 

 

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