1056634-68-4 Momelotinib

Specification:

Appearance	Off-White to Pale Yellow powder
Purity	98%+

 

Application:

Momolotinib (CYT387) is an ATP competitive JAK1/JAK2 inhibitor with an IC50 of 11 nM/18 nM, which is approximately 10 times more selective than acting on JAK3. Momelotinib is a novel oral JAK1/JAK2 and activator receptor type 1 (ACVR1) inhibitor primarily used to treat patients with myelofibrosis (MF) and anemia
 

Synonyms:

MOMELOTINIB

1056634-68-4

N-(Cyanomethyl)-4-(2-((4-morpholinophenyl)amino)pyrimidin-4-yl)benzamide

CYT-11387

momelotinibum

N-(Cyanomethyl)-4-(2-((4-morpholinophenyl)-amino)pyrimidin-4-yl)benzamide

CYT-0387

N-(cyanomethyl)-4-(2-((4-(4-morpholinyl)phenyl)amino)-4-pyrimidinyl)benzamide

 

 

 

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