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CAS 597562-32-8 | Antibacterial Protein LL-37;Antimicrobial Peptide, Human;

CAS 597562-32-8 | Antibacterial Protein LL-37;Antimicrobial Peptide, Human;

Name: Antibacterial protein LL-37 amide
CAS number: 597562-32-8
Molecular formula: C205H341N61O52
Molecular weight: 4492.27854
EINECS number: 200-001-8
MDL No.:MFCD08460571

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Description

Product Overview

Antibacterial protein LL-37 amide (CAS 597562-32-8) is a synthetic C-terminally amidated analog of the human cathelicidin host defense peptide LL-37. Consisting of 37 amino acids, this amphipathic alpha-helical peptide demonstrates broad-spectrum antimicrobial activity against Gram-positive and Gram-negative bacteria, fungi, and enveloped viruses, playing a major role in innate immune response and biomedical research.

Primary Applications & Characteristics

  • Antimicrobial & Antibiofilm Studies: Used in pharmacological research to evaluate bacterial membrane disruption, biofilm suppression, and resistance-defying therapeutic strategies.
  • Immunomodulation Research: Serves as a bioactive tool for investigating chemoattraction, inflammatory signaling pathways, and tissue regeneration mechanisms.
  • Wound Healing & Topical Formulations: Explored in preclinical models for promoting re-epithelialization and controlling localized microbial growth.
  • Enhanced Stability: C-terminal amidation provides increased resistance against enzymatic degradation by carboxypeptidases in physiological media.

Synonyms & Commercial Names

Antibacterial protein LL-37 amide; LL-37 amide; Antimicrobial Peptide LL-37, human amide; Cathelicidin LL-37 amide; Human LL-37 amide

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