1103522-45-7 Aprocitentan

Properties

Appearance White to Off-White powder
Melting point:139-141°C
Boiling point:705.0±70.0 °C 
Density 1.841±0.06 g/cm3
storage temp. -20°C  

 

Application:

      Aprocentan is a novel oral antihypertensive drug primarily used for the treatment of refractory hypertension. Aprocentan is a dual endothelin (ET) A/B receptor (ETA/ETB) antagonist that exerts antihypertensive effects by inhibiting the binding of ET-1 to ETA and ETB receptors
 

Synonyms:

Aprocitentan

1103522-45-7

Tryvio

Macitentan metabolite m6

N-[5-(4-bromophenyl)-6-{2-[(5-bromopyrimidin-2-yl)oxy]ethoxy}pyrimidin-4-yl]sulfuric diamide

Sulfamide, N-(5-(4-bromophenyl)-6-(2-((5-bromo-2-pyrimidinyl)oxy)ethoxy)-4-pyrimidinyl)-

N-(5-(4-Bromophenyl)-6-(2-((5-bromo-2-pyrimidinyl)oxy)ethoxy)-4-pyrimidinyl)sulfuric diamide

aprocitentanum

5-(4-bromophenyl)-4-(2-(5-bromopyrimidin-2-yl)oxyethoxy)-6-(sulfamoylamino)pyrimidine

 

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